Animated musical adventure following Scooby-Doo (voice of Frank Welker) and the Mystery, Inc. gang. Shaggy (Matthew Lillard), Fred (also Welker), Daphne (Grey DeLisle), Velma (Mindy Cohn) and Scooby decide to take a relaxing vacation after solving yet another mystery. They go to the 'Vampire Palooza' festival run by Vincent Van Helsing (Jeff Bennett) and are called into action when a troupe of vampire actors successfully perform a resurrection ritual on ancient vampire Valdronya. Things get worse, with the vampire on the loose, when Daphne is kidnapped and forced to marry Valdronya. Will the gang be able to save her before it's too late?